Regiospecific Organocatalytic Asymmetric Aldol Reaction of Methyl Ketones and α,β-Unsaturated Trifluoromethyl Ketones.
نویسندگان
چکیده
منابع مشابه
Asymmetric Organocatalytic Reactions of α, β-Unsaturated Cyclic Ketones
The 1,4-conjugate addition of nucleophiles to α,β-unsaturated carbonyl compounds represents one fundamental bond-forming reaction in organic synthesis. The development of effective organocatalysts for the enantioselective conjugate addition of malonate, nitroalkane and other carbon and heteroatom nucleophiles to cycloenones constitutes an important research field and has been explored in recent...
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Diastereoselective aldol additions have emerged as one of the most efficient and versatile methods available for preparing a wide range of optically active compounds.l Very high diastereoselectivities have been reported for aldol reactiona involving chiral enolates derived from a-ethylor higher alkyl-substituted ketone derivatives. By contrast, relatively few examples of highly diastereoselecti...
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ژورنال
عنوان ژورنال: ChemInform
سال: 2007
ISSN: 0931-7597,1522-2667
DOI: 10.1002/chin.200732067